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cGPS® Targeted Integration kits

Overexpress a transgene and generate isogenic & stable cell lines

Cellectis bioresearch offers cGPS® Targeted Integration (TI) kits to generate stable & isogenic cell clones (moncolonal or polyclonal populations) by overexpression of a transgene in your cell line of choice (including iPS cells).
We rely on proprietary know-how and exclusive rights regarding homologous recombination to bring engineered cell lines to your bench in the most cost and time efficient manner.

Available products

Carry out sequence-specific targeted integration to overexpress a transgene in any of the following:

Benefits

Guaranteed targeted integration

Fast

Robust and reliable data

Precise targeted integration to obtain your custom cell line

Increased cell line development productivity with less screening efforts due to high integration frequency (up to 98% efficiency)

Fast and effortless clone selection

As little as 20 days for monoclonal selection (polyclonal selection also available)

 

 

Controlled expression levels

Guaranteed stability of your cell clones without continuous addition of antibiotics (no drug interference)

True isogeny

One transgene copy integrated at one known expression site for comparable and reproducible results

Long compound testing campaigns

Highly stable expression over time (up to 22 weeks)

Related products & services

Not looking for an off the shelf product anymore?
If you would like to benefit from our in house know-how and team of experts, let us engineer for you your cell line of choice based on the cGPS® technology or cGPS® Custom technology.

For more information, please visit our Targeted Integration services page or contact us to discuss your project in more details.

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