Increase up to twice your gene knock-out efficiency

The TALEN™ KO Enhancer has been designed to increase TALEN™-induced mutagenesis when co-transfected with a TALEN™> plasmid. The TALEN™ KO Enhancer has an exonuclease activity that will increase TALEN™ induced mutation by a factor up to two and lead to larger deletions.

Available products

Product name Cat. No Description
TALEN™ KO Enhancer  KOEN-8982 TALEN™ KO Enhancer is distributed as a plasmid.

Benefits

Fast

Easy and guaranteed

Flexible

Screen less clones

Less screening needed due to higher mutagenesis activity

Increase KO gene editing project success

Increase KO frequency up to a factor of 3 without increase of off-target effects

Suitable for multiple allelic KO

Enhance potential for making multiple allelic KO in a single round of mutagenesis

Related products

Achieve best results for your gene knock-out project with TALEN™ Sure KO in combination with TALEN™ KO Enhancer.

TALEN™ Sure KO binds its recognition site within the first coding exon, inducing a DNA double-strand break at the recognition site, which is repaired by error prone non homologous end-joining.
To learn more about TALEN™ Sure KO, click here.

 

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